1.Intronic enhancers regulate the expression of genes involved in tissue-specific functions and homeostasis. Beatrice Borsari, Pablo Villegas-Miron,  Hafid Laayouni, Alba Segarra-Casas, Jaume Bertranpetit, Roderic Guigó,   Sandra Acosta*. 2020. BioRXiv.

 

2.A Human Accelerated Region participates in early human forebrain patterning and expansion. Sandra Acosta+, Luciano Fiore, Isabel  Rollan, Giovanni Iacono, Alexander V. Misharin, Nozomu Takata, Martin   Sikora   , Nikita Joshi, Beisi Xu, Eske Willerslev, Holger Heyn, Miguel ManzanaresGuillermo Oliver+.+Corresponding authors.2019.bioRxiv 777235

 

3.Adaptive Selection Drives Functional Changes In Trpp3 In Ethiopian Populations. Sandra Walsh, Mercè Izquierdo-Serra, Sandra Acosta, Maria  Lloret, Jaume Bertranpetit*, José Manuel FernándezFernández*. November   2020. Accepted Scientific Reports

 

4.Arl13b, a primary cilia scaffold protein, regulates eye morphogenesis through  Shh and Wnt signaling. Luciano Fiore*, Nozomu Takata*, Sandra  Acosta, Wanshu Ma, Tanushree Pandit, Guillermo Oliver. Developmental   Biology.462(2):119-128

 

5.Novel CRIPSR/Cas9-mediated high efficiency protocol for bi-allelic homologous recombination in mouse embryonic stem cells. Acosta S*, Fiore L,   Carota IA, Oliver G. Genesis. 2018 May;56(5):e23212. Corresponding author.

 

6.Human pluripotent stem cell-derived cortical neurons integrate functionally into the lesioned adult murine visual cortex in an area-specific way.  Espuny-  Camacho I, Michelsen KA, Linaro D, Bilheu A, Acosta-Verdugo S, Herpoel A, Giugliano M, Gaillard A, Vanderhaeghen P. Cell Reports. 2018   May 29;23(9):2732-2743

 

7.An mouse ESC-derived eye organoid approach identifies Six3 suppression of R-spondin 2 as a critical step in mouse neuroretina differentiation.  Takata N, Abbey D*, Fiore L*, Acosta S, Feng R, Gil HJ, Lavado A, Geng X, Interiano A, Neale G, Eiraku M, Sasai Y, Oliver G. Cell Reports. 2017 Nov   7;21(6):1534-1549, *Co-authors.

 

8.Six3 dosage mediates the pathogenesis of holoprosencephaly. Geng X, Acosta S, Lagutin O, Gil, HJ, Oliver, G. 2016. Development. 143(23):4462-   4473.Co-first author. Cover image.

 

9.Specific reestablishment of damaged neuronal pathways in the adult cerebral cortex following grafting of cortical neurons derived from mouse  embryonic stem cells.  Michelsen KA, Acosta-Verdugo S*, Benoit-Marand M, Espuny-Camacho I, Gaspard N, Saha B,  Gaillard, Pierre Vanderhaeghen.   2015, Neuron 85, 982–997 Co-first author.

 

10.A familial heterozygous null mutation of MET in autism spectrum disorder. Lambert N, Wermenbol V, Pichon B, Acosta S, van den Ameele J,  Perazzolo C, Messina D, Musumeci MF, Dessars B, De Leener A, Abramowicz M, Vilain C. Autism Res. 2014 Oct;7(5):617-22.

 

11.Identification of tumoral glial precursor cells in neuroblastoma. Acosta S, Mayol G, Rodríguez E, Lavarino C, de Preter K, Kumps C, Garcia I, de  Torres C, Mora J. Cancer Lett. 2011 Dec 15;312(1):73-81. First Author

 

12.Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells. Acosta S, Lavarino C,   Paris R, Garcia I, de Torres C, Rodríguez E, Beleta H, Mora J. BMC Dev Biol. 9:12 (2009) First author

 

13.The calcium-sensing receptor and parathyroid hormone-related protein are expressed in differentiated, favorable neuroblastic tumors. de Torres C,   Beleta H, Díaz R, Toran N, Rodríguez E, Lavarino C, García I, Acosta S, Suñol M, Mora J. Cancer. 115 (2009), 2792

 

14.Differential expression of genes mapping to recurrently abnormal chromosomal regions characterize neuroblastic tumours with distinct ploidy status.   Lavarino C, Garcia I, Mackintosh C, Cheung NK, Domenech G, Ríos J, Perez N, Rodríguez E, de Torres C, Gerald WL, Tuset E, Acosta S, Beleta H,   de   Alava E, Mora J. BMC Med Genomics. 1:36 (2008)

 

15.Use of the lambda Red recombinase system to produce recombinant prophages carrying antibiotic resistance genes. Serra-Moreno R, Acosta S,  Hernalsteens JP, Jofre J, Muniesa M. BMC Molecular Biology 7:31 (2006)